ÕÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍ͸ ³ ³ ³ ---Antianxiety Drugs--- ³ ³ ³ ³ A. Diazepam ³ ³ B. Hydroxyzine ³ ³ C. Lorazepam ³ ³ D. Meprobamate ³ ³ E. Prazepam ³ ³ F. Prozac ³ ³ ³ ÔÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍÍ; DIAZEPAM BRAND NAMES Apo-Diazepam Rival D-Tran Serenack E-Pam Stress-Pam Meval Valium Neo-Calme Valrelease Novodipam Vivol Q-Pam BASIC INFORMATION Habit forming? Yes Prescription needed? Yes Available as generic? Yes Drug class: Tranquilizer (benzodiazepine) USES Treatment for nervousness or tension Treatment for muscle spasm Treatment for convulsive disorders DOSAGE & USAGE INFORMATION More [Y,n,=]? = How to take: Tablet or capsule--Swallow with liquid. If you can't swallow whole, crumble tablet or open capsule and take with liquid or food. When to take: At the same time each day, according to instructions on prescription label. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose). What drug does: Affects limbic system of brain--part that controls emotions. Time lapse before drug works: 2 hours. May take 6 weeks for full benefit. Don't take with: See interaction column and consult doctor. POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS Symptoms What to do Life Threatening: None expected Common: Clumsiness, drowsiness Continue. Call doctor when dizziness convenient Infrequent: Hallucinations, confusion, Discontinue. Call doctor depression, irritability, right away rash, itch, vision changes Constipation or diarrhea, Continue. Call doctor when nausea, vomiting, difficult convenient. urination. Rare: Slow heartbeat, breathing Discontinue. Seek emergency difficulty treatment. Mouth, throat ulcers; jaundice Discontinue. Call doctor right away OVERDOSE Symptoms: Drowsiness, weakness, tremor, stupor, coma. What to do: Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately. If patient is unconscious and not breathing, give mouth-to-mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility. See emergency information. WARNINGS AND PRECAUTIONS Don't take if: You are allergic to any benzodiazepine. You have myasthenia gravis. You are active or recovering alcoholic. Patient is younger than 6 months. Before you start, consult your doctor: If you have liver, kidney or lung disease. If you have diabetes, epilepsy or porphyria. Over age 60: Adverse reactions and side effects may be more frequent and severe than in younger persons. You need smaller doses for shorter periods of time. May develop agitation, rage or "hangover" effect. Pregnancy: Risk to unborn child outweighs drug benefits. Don't use. Breast-feeding: Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply. Infants and Children: Use only under medical supervision for children older than 6 months. Prolonged use: May impair liver function. Skin & sunlight: No problems expected. Driving, piloting or hazardous work: Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes. Discontinuing: Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment. Others: Hot weather, heavy exercise and profuse sweat may reduce excretion and cause overdose. Blood sugar may rise in diabetics, requiring insulin adjustment. POSSIBLE INTERACTION WITH OTHER DRUGS Generic name or drug class Combined Effect _______________________________________________________________ Anticonvulsants Change in seizure frequency or severity. Antidepressants Increased sedative effect of both drugs. Antihypertensives Excessively low blood pressure. Cimetidine Excess sedation. Disulfiram Increased diazepam effect. Dronabinol Increased effects of both drugs. Avoid MAO inhibitors Convilsions, deep sedation, rage. Molindone Increased tranquilizer effect. Narcotics Increased sedative effect of both drugs. Sedatives Increased sedative effect of both drugs. Sleep inducers Increased sedative effect of both drugs. Tranquilizers Increased sedative effect of both drugs. POSSIBLE INTERACTION WITH OTHER SUBSTANCES Interacts with Combined Effect _________________________________________________________________ Aclohol Heavy sedation. Avoid. Beverages None expected. Cocaine Decreased diazepam effect. Foods None expected. Marijuana Heavy sedation. Avoid. Tobacco Decreased diazepam effect. HYDROXYZINE BRAND NAMES Anxanil Atarax Ataraxoid Atozine Cartrax Durrax Enarax E-Vista Hydroxacen Hy-Pam Hyzine Marax Multipax Neucalm 50 Orgatrax Quless T.E.H. Tablets Theozine Vamate Vistacon Vistaject Vistaquel Vistaril Vistazine Vistrax BASIC INFORMATION Habit forming? No Prescription needed? Yes Available as generic? Yes Drug class: Tranquilizer, antihistamine USES Treatment for anxiety, tension and agitation. Relieves itching from allergic reactions. DOSAGE & USAGE INFORMATION How to take: Tablet or capsule--Swallow with liquid. If you can't swallow whole, crumble tablet or open capsule and take with liquid or food. Liquid--If desired, dilute dose in beverage before swallowing. When to take: At the same times each day. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose). What drug does: May reduce activity in areas of the brain that influence emotional stability. Time lapse before drug works: 15 to 30 minutes. Don't take with: Non-prescription drugs without consulting doctor. See interaction column and consult doctor. POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS Symptoms What to do Life-threatening: None expected. Common: Drowsiness, difficult Continue. Tell doctor urination, dry mouth. at next visit. Infrequent: Headache Continue. Tell doctor at next visit. Rare: Tremor, rash Discontinue. Call doctor right away. OVERDOSE Symptoms: Drowsiness, unsteadiness, agitation, purposeless movements, tremor, convulsions. What to do: Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately. See Emergency Information WARNINGS AND PRECAUTIONS Don't take if: You are allergic to any antihistamine. Before you start, consult your doctor: If you have epilepsy. If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia. Over age 60: Adverse reactions and side effects may be more frequent and severe than in younger persons. Drug likely to increase urination difficulty caused by enlarged prostate gland. Pregnancy: Studies inconclusive on harm to unborn child. Animal studies show fetal abnormalities. Decide with your doctor whether drug benefits justify risk to unborn child. Breast-feeding: Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply. Infants & children: Use only under medical supervision. Prolonged use: Tolerance develops and reduces effectiveness. Skin & sunlight: No problems expected. Driving, piloting or hazardous work: Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs. Discontinuing: Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment. Others: No problems expected. POSSIBLE INTERACTION WITH OTHER DRUGS Generic Name or Drug Class Combined Effect Anticoagulants Increased anticoagulant (oral) effect Anticonvulsants Decreased anticonvulsant (hydantoin) effect. Antidepressants Increased effect of both (tricyclic) drugs. Antihistamines Increased hydroxyzine effect. Dronabinol Increased effects of both drugs. Avoid. Molindone Increased tranquilizer and antihistamine effect. Narcotics Increased effect of both drugs. Pain relievers Increased effect of both drugs. Sedatives Increased effect of both drugs. Sleep inducers Increased effect of both drugs. Tranquilizers Increased effect of both drugs. POSSIBLE INTERACTION WITH OTHER SUBSTANCES Interacts with: Combined Effect Alcohol: Increased sedation and intoxication. Use with caution. Beverages: Caffeine drinks Decreased tranquilizer effect of hydroxyzine. Cocaine: Decreased hydroxyzine effect. Avoid. Foods: None expected. Marijuana: None expected. Tobacco: None expected. LORAZEPAM BRAND NAMES Apo-Lorazepam Loraz Ativan Novolorazem BASIC INFORMATION Habit forming? Yes Prescription needed? Yes Available as generic? Yes Drug class: Tranquilizer (benzodiazepine) USES Treatment for nervousness or tension. DOSAGE & USAGE INFORMATION How to take: Tablet or capsule--Swallow with liquid. If yhou can't swallow whole, crumble tablet or open capsule and take with liquid or food. When to take: At the same time each day, according to instructions on prescription label. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose). What drug does: Affects limbic system of brain--part that controls emotions. Time lapse before drug works: 2 hours. May take 6 weeks for full benefit. Don't take with: See interaction column and consult doctor. POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS Symptoms What to do ________________________________________________________________ Life threatening: None expected Common: Clumsiness, drowsiness, Continue. Call doctor when dizziness convenient. Infrequent: Hallucinations, confusion, Discontinue. Call doctor depression, irritability, right away. itchy skin, rash, change in vision. Constipation or diarrhea, Continue. Call doctor when nausea, vomiting, difficult convenient. urination. Rare: Slow heartbeat, difficult Discontinue. Seek emergency breathing. treatment. Mouth, throat ulcers; Discontinue. Call doctor jaundice. right away. OVERDOSE Symptoms: Drowsiness, weakness, tremor, stupor, coma. What to do: Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately. If patient is unconscious and not breathing, give mouth-to-mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility. See emergency information. WARNINGS AND PRECAUTIONS Don't take if: You are allergic to any benzodiazepine. You have myasthenia gravis. You are active or recovering alcoholic. Patient is younger than 6 months. Before you start, consult your doctor: If you have liver, kidney or lung disease. If you have diabetes, epilepsy or porphyria. Over age 60: Adverse reactions and side effects may be more frequent and severe than in younger persons. You need smaller doses for shorter periods of time. May develop agitation, rage or "hangover" effect. Pregnancy: Risk to unborn child outweighs drug benefits. Don't use. Breast-feeding: Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply. Infants & Children: Use only under medical supervision for children older than 6 months. Prolonged use: May impair liver function. Skin & sunlight: No problems expected. Driving, piloting or hazardous work: Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes. Discontinuing: Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment. Others: Hot weather, heavy exercise and profuse sweat may reduce excretion and cause overdose. Blood sugar may rise in diabetics, requiring insulin adjustment. POSSIBLE INTERACTION WITH OTHER DRUGS Generic Name of Drug Class Combined Effect ______________________________________________________________ Anticonvulsants Change in seizure frequency or severity. Antidepressants Increased sedative effect of both drugs. Antihistamines Increased sedative effect of both drugs. Antihypertensives Excessively low blood pressure. Cimetidine Excess sedation. Disulfiram Increased Lorazepam effect. Dronabinol Increased effects of both drugs. Avoid. MAO inhibitors Convulsions, deep sedation, rage. Molindone Increased tranquilizer effect. Narcotics Increased sedative effect of both drugs. Sedatives Increased sedative effect of both drugs. Sleep inducers Increased sedative effect of both drugs. Tranquilizers Increased sedative effect of both drugs. POSSIBLE INTERACTION WITH OTHER SUBSTANCES Interacts with Combined Effect _______________________________________________________________ Alcohol Heavy sedation. Avoid. Beverages None expected. Cocaine Decreased lorazepam effect. Foods None expected. Marijuana Heavy sedation. Avoid. Tobacco Decreased lorazepam effect. MEPROBAMATE BRAND NAMES Apo-Meprobamate Miltown Miltown Arcoban Neo-Tran Bamate Neuramate Bamo 400 Novo-Mepro Coprobate Novomepro Deprol Pathibamate Equagesic Pax 400 Equanil PMB Equanil Wyseals Protran Evenol Quietal Kalmn Robam Lan-Dol Robamate Medi-tran Sedabamate Mep-E SK-Bamate Mepriam Tranmep MeproCompound Meprocon Meprospan Meprotabs Meribam BASIC INFORMATION Habit forming? Yes Prescription needed? Yes Available as generic? Yes Drug class: Tranquilizer USES Reduces mild anxiety, tension and insomnia. DOSAGE & USAGE INFORMATION How to take: Tablet or capsule--Swallow with liquid. Extended-release tablets ro capsules--Swallow each dose whole. If you take regular tablets, you may chew or crush them. Liquid--Take as directed on label. When to take: At the same time each day. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose). What drug does: Sedates brain centers which control behavior and emotions. Time lapse before drug works: 1 to 2 hours. Don't take with: Non-prescription drugs containing alochol or caffeine without consulting doctor. See interaction column and consult doctor. POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS Symptoms What to Do _______________________________________________________________ Life-threatening: None expected. Common: Dizziness, confusion, Continue. Tell doctor at agitation, drowsiness, next visit. unsteadiness, fatigue, weakness. Infrequent: Rash, hives, itchy skin; Discontinue. Call doctor change in vision; diarrhea, right away. nausea or vomiting. False sense of well-being, Continue. Call doctor when headache, slurred speech. convenient. Rare: Sore throat; fever; rapid, Discontinue. Call doctor pounding, unusually slow right away. or irregular heartbeat; difficult brething; unusual bleeding or bruising. OVERDOSE Symptoms: Dizziness, slurred speech, stagger, depressed breathing and heart function, stupor, coma. What to do: Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately. See emergency information on inside covers. WARNINGS AND PRECAUTIONS Don't take if: You are allergic to meprobamate, tybanate, carbromal or carisoprodol. You have had porphyria. Patient is younger than 6. Before you start, consult your doctor: If you have epilepsy. If you have impaired liver or kidney function. Over age 60: Adverse reactions and side effects may be more frequent and severe than in younger persons. Pregnancy: Risk to unborn child outweighs drug benefits. Don't use. Breast-feeding: Drug filters into milk. May harm child. Avoid. Infants & Children: Not recommended. Prolonged use: Habit forming. May impair blood-cell production. Skin and sunlight: No problems expected. Driving, piloting or hazardous work: Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs. Discontinuing: Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment. Others: No problems expected. POSSIBLE INTERACTION WITH OTHER DRUGS Generic Name or Drug Class Combined Effect _________________________________________________________________ Anticoagulants Decreased anticoagulant effect. Anticonvulsants Change in seizure pattern. Antidepressants Increased antidepressant effect. Contraceptives (oral) Decreased contraceptive effect. Dronabinol Increased effects of both drugs. Avoid. Estrogens Decreased estrogen effect. MAO inhibitors Increased meprobamate effect. Molindone Increased tranquilizer effect. Narcotics Increased narcotic effect. Sedatives Increased sedative effect. Sleep inducers Increased effect of sleep inducer. Terfenadine Possible excessive sedation. Tranquilizers Increased tranquilizer effect. POSSIBLE INTERACTION WITH OTHER SUBSTANCES Interacts with Combined Effect ______________________________________________________________ Alcohol Dangerous increased effect of meprobamate. Beverages: Caffeine drinks. Decreased calming effect of meprobamate. Cocaine: Decreased meprobamate effect. Foods: None expected. Marijuana: Increased sedative effect of meprobamate. Tobacco: None expected. PRAZEPAM BRAND NAME Centrax BASIC INFORMATION Habit forming? Yes Prescription needed? Yes Available as generic? No Drug class: Tranquilizer (benzodiazepine) USES Treatment for nervousness or tension. DOSAGE AND USAGE INFORMATION How to take: Tablet or capsule--Swallow with liquid. If you can't swallow whole, crumble tablet or open capsule and take with liquid or food. When to take: At the same time each day, according to instructions on prescription label. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose). What drug does: Affects limbic system, the part of the brain that controls emotions. Time lapse before drug works: 2 hours. May take 6 weeks for full benefit. Don't take with: See interaction column and consult doctor. POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS Symptoms What to do ____________________________________________________________________ Life-threatening: None expected. Common: Clumsiness drowsiness, Continue. Call doctor when dizziness. convenient. Infrequent: Hallucinations, confusion, Discontinue. Call doctor depression, irritability, right away. rash, itchy skin, change in vision. Constipation or diarrhea, Continue. Call doctor when nausea, vomiting, convenient. difficult urination. Rare: Slow heartbeat, difficult Discontinue. Seek emergency breathing. treatment. Mouth and throat ulcers, Discontinue. Call doctor jaundice. right away. OVERDOSE Symptoms: Drowsiness, weakness, tremor, stupor, coma. What to do: Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately. If patient is unconscious and not breathing, give mouth-to-mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility. See emergency information. WARNINGS AND PRECAUTIONS Don't take if: You are allergic to any benzodiazepine. You have myasthenia gravis. You have glaucoma. You are active or recovering alcoholic. Patient is younger than 6 months. Before you start, consult your doctor: If you have liver, kidney or lung disease. If you hve diabetes, epilepsy or porphyria. Over age 60: Adverse reactions and side effects may be more frequent and severe than in younger persons. You need smaller doses for shorter periods of time. May develop agitation, rage or "hangover" effect. Pregnancy: Risk to unborn child outweighs drug benefits. Don't use. Breast-feeding: Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply. Infants & children: Use only under medical supervision for children older than 6 months. Prolonged use: May impair liver function. Skin and sunlight: No problems expected. Driving, piloting or hazardous work: Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes. Discontinuing: Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment. Others: Hot weather, heavy exercise and profuse sweat may reduce excretion and cause overdose. Blood sugar may rise in diabetics, requiring insulin adjustment. POSSIBLE INTERACTION WITH OTHER DRUGS Generic Name or Drug Class Combined Effect ____________________________________________________________________ Anticonvulsants Change in seizure frequency or severity. Antidepressants Increased sedative effect of both drugs. Antihistamines Increased sedative effect of both drugs. Antihypertensives Excessively low blood pressure. Cimetidine Excess sedation. Disulfiram Increased prazepam effect. Dronabinol Increased effect of both drugs. Avoid. MAO inhibitors Convulsions, deep sedation, rage. Molindone Increased tranquilizer effect. Narcotics Increased sedative effect of both drugs. Sedatives Increased sedative effect of both drugs. Sleep inducers Increased sedative effect of both drugs. Tranquilizers Increased sedative effect of both drugs. POSSIBLE INTERACTION WITH OTHER SUBSTANCES Interacts with Combined effect ____________________________________________________________________ Alcohol Heavy sedation. Avoid Beverages None expected. Cocaine Decreased prazepam effect. Foods None expected. Marijuana Heavy sedation. Avoid. Tobacco Decreased prazepam effect. FLUOXETINE BRAND NAMES Prozac BASIC INFORMATION Habit forming? No Prescription needed? Yes Available as generic? No Drug class: Antidepressant USES Treats mental depression, particularly in people who do not tolerate tricyclic antidepressants. DOSAGE AND USAGE INFORMATION How to take: Capsules--Swallow with liquid or food to lessen stomach irritation. If you can't swallow whole, open capsule and take with liquid or food. When to take: In the morning at the same time each day. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose). What drug does: .Inhibits serotonin uptake in the central nervous system. .Causes loss of appetite. Time lapse before drug works: 1 to 3 weeks. Don't take with: .Any medicine that will change your level of consciousness or reflexes. .See interaction column and consult doctor. OVERDOSE Symptoms: Seizures. What to do: .Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately. .See emergency information. POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS Symptoms What to Do ___________________________________________________________________ Life-threatening: Rash, itchy skin, Seek emergency treatment breathing difficulty immediately. (allergic reaction), chest pain. Common: Diarrhea, nervousness, Continue. Call doctor when drowsiness, headache, convenient. increased sweating. Infrequent: Chills, fever, joint Disocntinue. Call doctor or muscle pain, right away. enlarged lymph glands, unusual excitability, blurred vision. Rare: .Convulsions. Discontinue. Seek emergency treatment. .Fast heartbeat. Discontinue. Call doctor abdominal pain. right away. .Nausea, vomiting, Continue. Call doctor when constipation, cough, when convenient. decreased appetite. ___________________________________________________________________ WARNINGS AND PRECAUTIONS Don't take if: You have severe liver or kidney disease. Before you start, consult your doctor: If you have history of seizure disorders. Over age 60: Adverse reactions and side effects may be more frequent and severe than in younger persons. You may need smaller doses for shorter periods of time. Pregnancy: No proven effects. Don't take unless essential. Breast-feeding: Unknown effects. Infants and Children: Not recommended. Prolonged use: No problems expected. Skin and sunlight: No problmes expected. Driving, piloting or hazardous work: Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes. Discontinuing: Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment. Others: No problems expected. POSSIBLE INTERACTION WITH OTHER DRUGS Generic name or drug class Combined Effect ___________________________________________________________________ Anticoagulants May cause confusion, agitation, convulsions, high blood pressure. Central nervous system Increases depressant effect (CNS) depressants of both drugs. Digitalis preparations May cause confusion, agitation, convulsions, high blood pressure. MAO inhibitors May cause confusion, agitation, convulsions, high blood pressure. Tryptophan Increased chance of agitation, restlessness, stomach upsets. ___________________________________________________________________ POSSIBLE INTERACTION WITH OTHER SUBSTANCES Interacts with Combined Effect ___________________________________________________________________ Alcohol: Possible toxicity of both drugs. Beverages: Decreases effect of fluoxetine. Cocaine: Decreases effect of fluoxetine. Foods: None expected. Marijuana: Decreases effect of fluoxetine. Tobacco: Decreases effect of fluoxetine. ___________________________________________________________________ Downloaded From P-80 International Information Systems 304-744-2253